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Regeneration powered by resorbable magnesium
Emergence Dental is a research and development-stage medical device company taking a dental-first approach to emerging new regenerative products from metallic magnesium alloys, that safely resorb when implanted in the body. Emergence Dental focuses on medical device design and pre-clinical development in collaboration with nanoMAG, LLC.
Speeding time to dental implant placement
Emergence Dental’s magnesium regenerative products address the 50% of dental implant procedures that require bone grafting to build a strong bony foundation
Providing soft tissue friendly form stability
Emergence Dental’s magnesium regenerative products combine the strength of metals with the soft-tissue friendliness of current resorbable barrier membranes
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Scientific Highlights
- Porous magnesium/PLGA composite scaffolds for enhanced bone regeneration following tooth extraction
- Authors: Andrew Brown, Saer Zaky, Herbert Ray Jr., Charles Sfeir
- Journal: Acta Biomaterialia
- Summary: Porous magnesium-polymer bone grafting scaffolds were produced and shown to permit a controlled resorption of the magnesium/polymer device. When implanted in a canine ridge preservation model, the magnesium-polymer scaffolds showed enhanced bone regeneration compared to controls.
- doi:10.1016/j.actbio.2014.09.008
- In vivo study of magnesium plate and screw degradation and bone fracture healing
- Authors: Amy Chaya, Sayuri Yoshizawa, Kostas Verdelis, Nicole Myers, Bernard J. Costello, Da-Tren Chou, Siladitya Pal, Spandan Maiti, Prashant N. Kumta, Charles Sfeir
- Journal: Acta Biomaterialia
- Summary: Magnesium fracture fixation plates and screws were manufactured and used to fixate simulated fractures in a rabbit ulna. When assessed by mechanical testing, there was no difference in flexural load in the healed ulnae compared to intact ulnae. Additionally, microCT analysis showed fracture healing and bone formation round the magnesium devices.
- doi:10.1016/j.actbio.2015.02.010
Scientifically Driven
Emergence Dental’s technologies are built on a foundation of strong basic scientific and translational research studies